Apigenin inhibits proliferation of ovarian cancer A2780 cells through Id1

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Apigenin inhibited migration and invasion of human ovarian cancer A2780 cells through focal adhesion kinase.

Apigenin, a common dietary flavonoid, has been found to have antitumor properties and therefore poses special interest for the development of chemopreventive and/or chemotherapeutic agent for cancers. Here, we demonstrate that apigenin inhibits expression of focal adhesion kinase (FAK) and migration and invasion of human ovarian cancer A2780 cells. FAK is a non-receptor protein tyrosine kinase ...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 2009

ISSN: 0014-5793

DOI: 10.1016/j.febslet.2009.05.013